One pill. Once a day.
All-day effectiveness.
Now your patients can get the same effective treatment for urinary incontinence (UI) due to urethral sphincter hypotonus that you’ve come to trust from PROIN® in a convenient, once-a-day dose with PROIN ER™ (phenylpropanolamine hydrochloride extended-release tablets).
Thanks to the controlled release mechanism in our patented extended-release technology, PROIN ER™ maintains steady absorption throughout the day. Plus, there’s no washout period when transitioning from PROIN to PROIN ER. Factor in its delicious liver flavoring, and it all adds up to improved compliance and happier dogs and families.
Easy to prescribe weight-band dosing
of owners, when asked on Day 28, assessed their dog as “improved” or “stayed the same.”1
of doses voluntarily consumed when given without or with a small amount of food.1
PROIN ER™ by the numbers
PROIN ER is an effective, easy-to-use treatment of UI due to urethral sphincter hypotonus in spayed, female dogs.
The PROIN ER™ advantage
1x per day
One extended-release tablet per day can be conveniently given with food.
Accurate dosing
Available in four weight-based strengths for accurate dosage of virtually any sized dog weighing 10 pounds or more. See prescribing information for details.
Enticing flavor
Delicious tablets improve compliance and make treatment easy.
Steady absorption
Patented extended-release technology provides controlled release that ensures steady absorption.
FDA-approved
The only once-a-day, FDA-approved medication for the control of urinary incontinence due to urethral sphincter hypotonus in dogs.
Convenient packaging
30 ct. & 90 ct. bottles are conveniently sized for storage and dosing.
1x per day
One extended-release tablet per day can be conveniently given with food.
Accurate dosing
Available in four weight-based strengths for accurate dosage of virtually any sized dog weighing 10 pounds or more. See prescribing information for details.
Enticing flavor
Delicious tablets improve compliance and make treatment easy.
Steady absorption
Patented extended-release technology provides controlled release that ensures steady absorption.
FDA-approved
The only once-a-day, FDA-approved medication for the control of urinary incontinence due to urethral sphincter hypotonus in dogs.
Convenient packaging
30 ct. & 90 ct. bottles are conveniently sized for storage and dosing.
What is urinary incontinence?
Urinary incontinence (UI) occurs when dogs involuntarily lose urine due to lack of bladder control. It typically starts 2-4 years after a female dog is spayed, but can begin sooner or later. Medium to large breed dogs are commonly affected, but small breed dogs may also develop urinary incontinence.1,2
Signs of urinary incontinence (UI):
• Dripping, leaking urine • Wet spots where dog sleeps • Excessive licking of genitals • Red, irritated skin in the genital area • Inappropriate urination indoors
2Holt PE, Thrusfield MV. Association in bitches between breed, size, neutering and docking, and acquired urinary incontinence due to incompetence of the urethral sphincter mechanism. Vet Rec 1993;133:177–180.
Additional resources
See below for more information regarding PROIN ER™ and canine urinary incontinence (UI) including prescribing information, articles and videos, and a helpful checklist for dog owners when talking to their veterinarian.
Prescribing information
Prescribing information for PROIN ER for the treatment of UI due to urethral sphincter hypotonus.
Articles and videos
Learn more about UI, its causes and the effectiveness of PROIN ER.
Discussion guide
Veterinary resources
Valuable information and insights from veterinary experts about canine UI and PROIN ER.
Pet Owner Brochure
A downloadable PDF highlighting the features and benefits of PROIN ER.
Since urinary incontinence may be new to you, here’s a helpful list of questions your veterinarian may ask to help in the diagnosis (along with performing tests like urine culture, blood tests, abdominal imaging, or ultrasound). Answering these questions before the first appointment could be the first step in managing your dog’s leaking issues.
Is PROIN ER™ right for your dog?
Since urinary incontinence may be new to you, here’s a helpful list of questions your veterinarian may ask to help in the diagnosis (along with performing tests like urine culture, blood tests, abdominal imaging, or ultrasound). Answering these questions before the first appointment could be the first step in managing your dog’s leaking issues.